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The error code can pop up anytime. You can’t prevent the error code from getting displayed on your screen. But whenever you notice the error code, then you must save your work at the earliest or it may lead to data loss. 

The <[pii_email_a5e6d5396b5a104efdde]> is a system-generated MS Outlook error code. It has nothing to do with your PC or any of the hardware connected to it.